Chin-Shang Li, PhD

Professor

portrait of Chin-Shang Li.

ADDRESS:
 School of Nursing
University at Buffalo
201 B Wende Hall
Buffalo, NY 14214-8013

PHONE: 716-829-3344

EMAIL: chinshan@buffalo.edu

I develop statistical methodologies to deal with statistical questions and issues arising from collaborative research so that these methodologies can be implemented in statistical software.

Chin-Shang Li has published extensively throughout his professional career. In addition to collaborations with many health science and medical researchers from an array of institutions and organizations, Li also has extensive editorial experience. He is editor-in-chief for three peer-reviewed journals: International Journal of Statistics and Probability; Current Research in Biostatistics; and Biostatistics and Metrics. He is also an editorial board member for several other academic journals. 

Prior to the University at Buffalo, Li was a professor in the Division of Biostatistics, Department of Public Health Sciences, at the University of California Davis School of Medicine. His main responsibilities in this role included research, teaching and provision of statistical support of clinical trials, as well as grant submissions and statistical analysis in several areas. These include, but are not limited to, anesthesiology and pain medicine; biomedical engineering; breast cancer; dermatology; nuclear medicine; obstetrics and gynecology; pediatrics; pharmacy; psychiatry and behavioral sciences; and veterinary surgical and radiological sciences.

Education

  • PhD, Statistics, Texas A&M University
  • MS, Applied Mathematics, National Chung Hsing University (Taichung, Taiwan)
  • BS, Applied Mathematics, National Chung Hsing University (Taichung, Taiwan)

Areas of Research

  • Cure models (including survival analysis)
  • Statistical methodology for zero-inflated count data
  • Semiparametric and nonparametric regression
  • Generalized linear models
  • Longitudinal data analysis
  • Clinical trial design
  • Large sample theory

Teaching Responsibilities

  • NUS 694 Quantitative Methods in Health Care Research
  • NUS 695 Advanced Statistical Techniques
  • NUS 706 Psycho-Social Measurement and Questionnaire Construction

Recent Publications

Dickerson, S. S., TenBrock, E., Smith, P., Kwon, M., Chacko, T., Li, C.-S., & Dean, G. E. (2020). Mixed methods feasibility study of Breathe2Sleep™ a peer modeling approach to PAP self-management. The Journal of Cardiopulmonary and Acute Care: Heart & Lung. Advance online publication. https://doi.org/10.1016/j.hrtlng.2020.04.015

Lu, M., Liu, Y., &  Li, C.-S. (2020). Efficient estimation of a linear transformation model for current status data via penalized splines. Statistical Methods in Medical Research, 29(1), 3-14. https://doi.org/10.1177/0962280218820406

Brown, E. G., Bateni, S. B., Burgess, D., Li, C.-S., & Bold, R. J. (2019). Interhospital variability in quality outcomes of pancreatic surgery. Journal of Surgical Research, 235, 453-458. https://doi.org/10.1016/j.jss.2018.10.035

Dyer, B. A., Li, C.-S., Daly, M. E., Monjazeb, A. M., & Mayadev, J. S. (2019). Prospective, randomized control trial investigating the impact of a physician-communicated radiation therapy plan review on breast cancer patient-reported satisfaction. Practical Radiation Oncology, 9(6). https://doi.org/10.1016/j.prro.2019.06.004 

Lu, M. Liu, Y., & Li, C.-S. (2019). Efficient estimation of linear transformation models with current status data via penalized splines. Statistical Methods in Medical Research. Advance online publication. https://doi.org/10.1177/0962280218820406

Maguire, F. B., Morris, C. R., Parikh-Patel, A., Cress, R. D., Keegan, T. H. M, Li, C.-S., … Kizer, K. W. (2019). Disparities in systemic treatment use in advancedstage non-small cell lung cancer by source of health insurance. Cancer Epidemiology, Biomarkers & Prevention. Advance online publication. https://doi.org/10.1158/1055-9965.EPI-18-0823

Maguire, F. B., Morris, C. R., Parikh-Patel, A., Cress, R. D., Keegan, T. H. M., Li, C. S., Lin, P. S., & Kizer, K. W. (2019). First-line systemic treatments for stage IV non-small cell lung cancer in California: Patterns of care and outcomes. JNCICS: Journal of the National Cancer Institute Cancer Spectrum. Advance online publication. https://doi.org/10.1093/jncics/pkz020

Li, C. S., Lee, S. M., & Yeh, M. S. (2019). A test for lack-of-fit of zero-inflated negative binomial models. Journal of Statistical Computation and Simulation, 89(7), 1301-1321. https://doi.org/10.1080/00949655.2019.1577856

Maguire, F. B., Morris, C. R., Parikh-Patel, A., Cress, R. D., Keegan, T. H. M., Li, C. S., Lin, P. S., & Kizer, K. W. (2019). A text-mining approach to obtain detailed treatment information from free-text fields in population-based cancer registries: A study of non-small cell lung cancer in California. PLOS ONE, 14(2): e0212454. doi:10.1371/journal.pone.0212454

Wang, E. B., Kaur, R., Nguyen, J., Ho, D., Austin, E., Maverakis, E., Li, C.-S., … Jagdeo, J. (2019). A single-blind, dose-escalation, phase I study of high-fluence light-emitting diode-red light on Caucasian non-Hispanic skin: Study protocol for a randomized controlled trial. Trials, 20(1), 177. https://doi.org/10.1186/s13063-019-3278-7

Wu, H.-Y., Ma, M.-C., Pan, Y.-Y., Shih, C.-L., Zgoda, V., Li, C.-S., Lin, L.-C., & Liao, P.-C. (2019). Assessing the similarity between random copolymer drug glatiramer acetate by using LC-MS data coupling with hypothesis testing. Analytical Chemistry, 91(22), 14281-14289. https://doi.org/10.1021/acs.analchem.9b02488

Foster, B., Boutin, R. D., Lenchik, L., Gedeon, D., Liu, Y., Nittur, V., Badawi, R. D., Li, C. S., Canter, R. J., & Chaudhari, A.J. (2018). Skeletal muscle metrics on clinical18 F-FDG-PET/CT predict health outcomes in patients with sarcoma. Journal of Nature and Science, 4(5), e502.

Hwang, H. V., Lin, Y., Rebuffatti, M. N., Tran, D. T., Lee, L., Gomes, A. V., Li, C.-S., & Knowlton, A. A. (2019). Impaired proteostasis in senescent vascular endothelial cells: A perspective on estrogen and oxidative stress in the aging vasculature. American Journal of Physiology - Heart and Circulatory Physiology, 316(2), H421-H429. https://doi.org/10.1152/ajpheart.00318.2018

Hwang, H. T. V., Lin, Y., Rebuffatti, M. N., Tran, D. T., Lee, L., Gomes, A., Li, C. S., & Knowlton, A. (2019). Contribution of oxidative stress and estrogen loss to impaired proteostasis and a diminished heat shock response in senescent vascular endothelial cells: A perspective on estrogen and oxidative stress in the aging vasculature. AJP-Heart and Circulatory Physiology, 316(2), H421-H429. doi:10.1152/ajpheart.00318.2018

Henderson, T., Chen, M. Darrow, M. A., Li, C. S., Chiu, C. L., Monjazeb, A. M., Murphy, W. J., & Canter, R. J. (2018). Alterations in cancer stem-cell marker CD44 expression predict oncologic outcome in soft-tissue sarcomas. Journal of Surgical Research, 223, 207-214. doi:10.1016/j.jss.2017.11.016

Hwang, H. T. V., Tran, D. T., Rebuffatti, M. N., Li, C. S., & Knowlton, A. A. (2018). Investigation of quercetin and hyperoside as senolytics in adult human endothelial cells. PLOS ONE, 13(1), e0190374. https://doi.org/10.1371/journal.pone.0190374

Lu, M., Liu, Y., & Li, C. S. (2018). Efficient estimation of linear transformation models with current status data via penalized splines. Statistical Methods in Medical Research. Advance online publication. doi:10.1177/0962280218820406

Ram, S., Sarma, N., Lopez, J. E., Liu, Y., Li, C. S., & Aminololama-Shakeri, S. (2018). Impact of the California breast density law on screening breast MR utilization, provider ordering practices and patient demographics. Journal of the American College of Radiology, 15(4), 594-600. doi:10.1016/j.jacr.2017.12.001

Tentindo, G. S., Fishman, S., Li, C. S., Wang, Q., & Brass, S. D. (2018). The prevalence and awareness of sleep apnea in patients suffering chronic pain: An assessment using the STOP-Bang sleep apnea questionnaire. Nature and Science of Sleep, 10, 217-224. doi:10.2147/NSS.S167658

Tong, E. K., Saw, A., Fung, L. C., Li, C. S., Liu, Y., & Tsoh, J.Y. (2018). Impact of a smoke-free-living educational intervention for smokers and household nonsmokers: A randomized trial of Chinese American pairs. Cancer, 124 (57), 1590-1598.

Walker, C. K., VandeVoort, C. A., Li, C. S., Chaffin, C. L., & Capitanio, J. P. (2018). Adiposity and weight gain during pregnancy associate independently with behavior of infant rhesus monkeys (Macaca mulatta). Developmental Psychobiology, 60(6), 629-638. doi:10.1002/dev.21744

Wu, Y., Lin, Y., Lu, S. E., Li, C. S., & Shih, W. J. (2018). An extended semi-parametric accelerated failure time cure model for partial cure information known. Current Research in Biostatistics, 8, 9-19. doi:10.3844/amjbsp.2018.9.19

Yanagisawa, M. Gingrich, A. A., Judge, S., Li, C. S., Wang N., Thorpe, S. W., Kirane, A. R., Bold, R. J., Monjazeb, A. M., & Canter, R.J. (2018). Serum C-reactive protein and neutrophil/lymphocyte ratio after neoadjuvant radiotherapy in soft tissue sarcoma. Anticancer Research, 38, 1491-1497.

Yeo, K. K., Armstrong, E. J., Lopez, J. E., Chen, D. C., Westin, G. G., Li, C. S., Anderson, D., Hua, A., Singapuri, A., Amsterdam, E. A., Chiamvimonvat, N., & Laird, J. R. (2018). Aspirin and clopidogrel high on-treatment platelet reactivity and genetic predictors in peripheral arterial disease. Catheterization and Cardiovascular Interventions, 91(7), 1308-1317. doi:10.1002/ccd.27453

Behrends, C.N., Li, C.S., and Gibson, D.R. (2017). Decreased odds of injection risk behavior associated with direct versus indirect use of syringe exchange: evidence from two California cities. Substance Use and Misuse, 52(9), 1151-1159. doi:10.1080/10826084.2017

Chau, T., Parsi, K. K., Ogawa, T., Kiuru, M., Konia, T., Li, C. S., & Fung, M. A. (2017). Psoriasis or not? Review of 51 clinically co rmed cases reveals an expanded histopathologic spectrum of psoriasis. Journal of Cutaneous Pathology, 44(12), 1018-1026. https://doi.org/10.1111/cup.13033

Davari, P., Millsop, J. W., Johnson, M. A. N., Takahashi, S. R., Peng, D. H., Badger, J., Bahr, B. A., Shinkai, K., Li, C.S., & Fazel, N. (2017). Dermatology medical education: A multicenter survey study of the undergraduate perspective of the dermatology clinical clerkship. Dermatology Online Journal, 23(12), 2.

David, E. A., Daly, M. E., Li, C. S., Chiu, C. L., Cooke, D. T., Brown, L. M., Melnikow, J., Kelly, K., & Canter, R.J. (2017). Increasing rates of no treatment in advanced-stage non-small cell lung cancer patients: A propensity-matched analysis. Journal of Thoracic Oncology, 12, 437-445. doi:10.1016/j.jtho.2016.11.2221

Enkhmaa, B., Anuurad, E., Zhang, W., Li, C. S., Kaplan, R., Lazar, J., Merenstein, D., Karim, R., Aouizerat, B., Cohen, M., Butler, K., Pahwa, S., Ofotokun, I., Adimora, A. A., Golub, E., & Berglund, L. (2017). Lp(a) and HIV: Allele-spec c apolipoprotein(a) levels predict carotid intimamedia thickness in HIV-infected young women in the Women's Interagency HIV Study. Arteriosclerosis, Thrombosis and Vascular Biology, 37(5), 997-1004. doi: 10.1161/ATVBAHA.117.309137

Enkhmaa, B., Anuurad, E., Zhang, W., Yue, K., Li, C.S., and Berglund, L. (2017). The roles of apo(a) size, phenotype, and dominance pattern in PCSK9-inhibition-induced reduction in Lp(a) with alirocumab. Journal of Lipid Research, 58(10), 2008-2016. doi:10.1194/jlr.M078212

Foolad, N., Ornelas, J. N., Clark, A. K., Ali, I., Sharon, V. R., Mubarak, L. A., Lopez, A., Alikhan, A., Dabagh, B., Firooz, A., Awasthi, S., Liu, Y., Li, C. S., & Sivamani, R. K. (2017). International inter-rater agreement in scoring acne severity utilizing cloud-based image sharing of mobile phone photographs. International Journal of Dermatology, 56, 920-925. doi:10.1111/ijd.13621

Gingrich, A. A., Elias, A., Lee, C. Y. M., Nakache, Y. P. N., Li, C. S., Shah, D. R., Boutin, R. D., & Canter, R. J. (2017). Predictors of residual disease after unplanned excision of soft tissue sarcomas. Journal of Surgical Research, 208, 26-32.

Jha, P., Melendres, G., Bijan, B., Ormsby, E., Chu, L.L., Li, C.S., and McGahan, P.J. (2017). Trauma in pregnant women: Assessing detection of post-traumatic placental abruption on contrast-enhanced CT versus Ultrasound. Abdominal Radiology, 42(4), 1062-1067. doi:10.1007/s00261-016-0970-x

Jones, J. H., Singh, N., Nidecker, A., Li, C. S., & Fishman, S. (2017). Assessing the agreement between radiologic and clinical measurements of lumbar and cervical epidural depths in patients undergoing prone interlaminar epidural steroid injection. Anesthesia and Analgesia, 124(5), 1678-1685. doi:10.1213/ANE.0000000000001839

Kamangar, F., Davari, P., Azari, R., Fitzmaurice, S., Li, C. S., Eisen, D. B., & Fazel, N. (2017). The residency interview is still paramount: results of a retrospective cohort study on concordance of dermatology residency applicant evaluators and infuence of the applicant interview. Dermatology Online Journal, 23(5), 22.

Kamangar, F., Petukhova, T. A., Monico, G., Mathis, S., Joo, J., Zhuang, A., Li, C. S., Liu, Y., Lee, E., & Eisen, D. (2017). Anxiety level of patients undergoing common dermatologic procedures versus those seeking general dermatologic care. Dermatology online Journal, 23(5), 19.

Loja, M. N., Sammann, A., DuBose, J., Li, C. S., Liu, Y., Savage, S., Scalea, T., Holcomb, J. B., Rasmussen, T. E., Knudson, M. M., & the AAST PROOVIT Study Group. (2017). The mangled extremity score and amputation: time for a revision. Journal of Trauma and Acute Care Surgery, 82(3), 518-523. doi:10.1097/TA.0000000000001339

Mayadev, J., Li, C. S., Lim, J., Valicenti, R. V., & Alvarez, E. A. (2017). Alcohol abuse decreases pelvic control and survival in cervical cancer: an opportunity of lifestyle intervention for outcome improvement. American Journal of Clinical Oncology, 40(5), 451-457. doi:10.1097/COC.0000000000000187

Mayadev, J., Viswanathan, A., Liu, Y., Li, C. S., Alburquerque, K., Damato, A.L., Beriwal, S., & Erickson, B. (2017). American Brachytherapy Task Group Report: A pooled analysis of clinical outcomes for high-dose-rate brachytherapy for cervical cancer. Brachytherapy, 16, 22-43. doi:10.1016/j.brachy.2016.03.008

Nguyen, L. P., Beck, E., Cayetano, K., Li, C. S., & Hardin, K. (2017). Differential pulmonary rehabilitation outcomes in patients with and without COPD: role of gender. Journal of Cardioplumonary Rehabilitation and Prevention, 37, 350-355. doi:10.1097/HCR.0000000000000275

Patel, N. B., Coombs, D. M., Arsalai, M., Li, C. S., Liu, Y., Stevenson, T. R., & Pu, L. L. Q. (2017). The plastic surgeon as employee: a pilot survey of the California society of plastic surgeons. Annals of Plastic Surgery, 78(5), S238-S242.

Tchanque-Fossuo, C. N., Dahle, S. E., Lev-Tov, H., Li, C. S., & Isseroff, R. R. (2017). Cellular versus acellular grafts for diabetic foot ulcers: A protocol update for a comparative efficacy trial. Cutis, 100(5), E18-E21.

Honors & Awards

  • Caffey Award (John Kirkpatrick Young Investigator Award), The Society for Pediatric Radiology, 2005

Professional Activities

  • Editor-in-Chief, International Journal of Statistics and Probability
  • Editor-in-Chief, Current Research in Biostatistics
  • Editor-in-Chief, Enliven: Biostatistics and Metrics
  • Special Methodology Panel Member, Journal of General Internal Medicine
  • Editorial Board Member, Pioneer Journal of Theoretical and Applied Statistics
  • Editorial Board Member, Annals of Biometrics & Biostatistics
  • Academic Editor, Journal of Probability and Statistics
  • Editorial Board Member, Austin Biometrics and Biostatistics
  • Editorial Board Member, Journal of Health Education Research & Development